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Hunted down like prey and always on the run, the mutant half-siblings James Logan and Victor Creed roam the earth for nearly two centuries. Having survived an endless string of devastating wars thanks to their incredible regenerative and self-healing abilities, the brothers eventually part ways when Colonel William Stryker offers them a chance at redemption. However, against the backdrop of a personal loss, Logan will also confront an even bigger challenge - one that brings him head-to-head with the ugly face of retribution, and a technologically enhanced mighty adversary. Has the wild Wolverine the tools to vanquish him?