The Boy in the Plastic Bubble (1976)

Midteen Tod Lubitsch has spent his entire life either in the hospital, in his bedroom at his parents Johnny and Mickey Lubitch's home, or in the portable transporter between the two as he was born and still suffers from immune deficiency, with any illness potentially life threatening, thus each one of those environments literally being an enclosed plastic bubble to prevent any germs from entering his living environment. Johnny and Mickey knew he being immune compromised was a possibility based on the experience of Mickey's first pregnancy, the fetus which did not survive the term. Dr. Gunther, an immunologist, has worked on Tod's case Tod's entire life, and while certain progress has been made both in science and in Tod's own development of some immunity within himself, Dr. Gunther has no idea if there will ever be a time if it will be safe for Tod to enter a "germ-filled" world without those physical precautions. In puberty, Tod becomes more and more interested in experiencing the outside world first-hand, especially as he has his first case of puppy love with longtime neighbor, same aged Gina Biggs, who he can often see from his bedroom window and is the only person his age he has ever had contact with in she invited annually into their home for Tod's birthday.