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New York City. Psychiatrist Dr. Sam Foster has temporarily taken over the therapy sessions for college student Henry Letham in the absence of Henry's regular therapist, Sam's friend Dr. Beth Levy. To Sam, Henry does not come across as extraordinary compared to any of his other patients, that is until a passing comment by Henry that seemed unlikely to happen actually does. But it is during Sam's second meeting with Henry that some of Henry's issues come to light: that he is having trouble differentiating between what is real and what isn't, and that he makes the statement that he will kill himself in exactly three days at midnight. As Sam starts to investigate Henry's case more deeply in order to help him and find out the underlying causes for Henry wanting to kill himself at that specific time and date to prevent it from happening, Sam starts coming across situations which seem a little odd to him, both related to Henry's case and in his life outside of the case and outside of work. At first, Sam believes these odd occurrences are just misunderstandings on his part or something odd with the other people involved. However, Sam ultimately comes to believe that he too is having trouble differentiating between what is real and what isn't as some things he believes to have happened he knows realistically could not have. The only thing he knows is that he loves his girlfriend, artist Lila Culpepper who was once his patient and who once tried to commit suicide. In wanting to marry her, he knows that she will never try to kill herself again because of the mutual love they have for each other. But even his life with Lila may not end up being as it seems to him if he is ever to discover what is truly reality and what is happening to Henry.