Frantic (1988)

Prominent American surgeon Dr. Richard Walker travels to a medical conference in Paris with his wife, Sondra. The first time they went to Paris was for their honeymoon and now they intend to celebrate the return to there. In their hotel room, Richard realizes that Sondra brought a wrong suitcase. He takes a shower, she receives a phone call, and leaves the room. He sleeps and when he wakes up, he realizes that she is missing. Soon he discovers that she was kidnapped, and he contacts the French police and American embassy, but he does not feel any interest in the agents to search for her. He decides to investigate and soon he meets the suitcase's owner, a small-time drug smuggler named Michelle that decides to help him to find Sondra in the underground of Paris.